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They have exploded in popularity online, with influencers suggesting they can help build muscle, improve metabolism and more

This may directly affect gene transcription or recruit transcription factors to specific promoter regions

The strongest clinical use cases are metabolic slowdown, fatigue, exercise intolerance, insulin resistance, and visceral fat in patients who have plateaued with diet and training alone

Less frequent sessions may be more effective Finding: Reducing microneedling session frequency (e.g., fortnightly rather than weekly) showed a positive influence on treatment outcomes

U.KimE.et al (2022)